Nice article thanks for posting, not much has changed in our understanding of Parkinson’s since I first studied it as a young biochemist some 3 decades ago prior to entering medical school. Unfortunately what Doctor Lowe said about the human body being a lot more complex than silicon is very true. Human and biological systems involve a level of parallelism that make microprocessors look like a piece of cake. And unfortunately the easy stuff or low lying fruit is often discovered first, levo dopa was the low lying fruit in the case of Parkinson’s, but its remarkable how it can add decades of quality life to a person. The way most disease processes are being handled these days is basically we are nickel and diming them to squeeze more answers and quality of life out of them. We are all fortunate Andy Grove is tackling Parkinson’s with his usual zeal something good has already come from his misfortunate.