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Replies to #53484 on Biotech Values
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rfj1862

10/15/07 9:11 PM

#53485 RE: ThomasS #53484

RPRX

I posted this on the RPRX board too, but for those of you who don't read it....

This is funny. I've pasted below the Reuters report on the recent news that appeared in my E*Trade account. Now, if you read this and didn't know better (a category under which the majority of retail falls) wouldn't you think this was bad news? Especially the headline.

Might be a brief selloff tomorrow morning before the real news sinks in, depending on how many people read only this.

Whoever writes biotech news at Reuters should be shot. Or do they have a computer program writing this kind of stuff? I know they do for earnings releases.



Repros to revise testosterone drug trial design
Reuters - October 15, 2007 8:25 PM ET

NEW YORK, Oct 15 (Reuters) - Repros Therapeutics Inc (RPRX) said on Monday it plans to submit a revised protocol for future clinical trials of its experimental drug Androxal to treat testosterone deficiency, following discussions with U.S. health regulators.

"We believe Androxal may have the potential to reach a broader spectrum of endocrinological dysfunctions beyond the effects of low testosterone alone," said Chief Executive Joseph Podolski. (Reporting by Martinne Geller)
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rfj1862

10/15/07 9:13 PM

#53486 RE: ThomasS #53484

>As for the unmasking prostate part, it only normalizes T. (as you know).<

I know. But fact is testosterone levels decline naturally as men age. So raising testosterone levels to a physiologic "normal" of a 30-year-old man in a 70-year-old does have the potential to unmask prostate cancer. I don't think there's any doubt about that.

I suspect that the label will contain a black box to this effect and a recommendation to monitor PSA at 6-month intervals.

I should note, however, that there is probably less potential for Androxal to unmask PC as it's not possible to attain supraphysiologic plasma levels with Androxal.
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DewDiligence

10/15/07 10:14 PM

#53499 RE: ThomasS #53484

Where do you see RPRX ending the day tomorrow (Tue)?