Pfizer usually has a contest to see who can name the drug. I participated in the naming of atorvastatin + amlodipine, although my admittedly crappy suggestions didn't win.
The winner, of course, was Caduet (CAD = coronary artery disease; duet = the combo of atorvastatin and amlodipine). Brilliant name, not so brilliant product.
Drug naming: another factor that didn't exist 2 decades ago is that any new name would also have to have a URL available. You simply can't name a drug Lunesta unless you also own www.Lunesta.com....or be able to buy it.