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sunstar

09/28/07 11:13 AM

#17379 RE: EZLibra #17366

EZ, that’s what I’m taking away from this too.

“Although sterile protection against a simian human immunodeficiency virus (SHIV) challenge has been described in monkeys infused with neutralizing monoclonal antibodies, these antibodies must be present at extraordinarily high titers in the experimental animals.”

Full dosing of the bavi antibody covering the PS will allow the innate and adaptive immunity to occur. Then…

If we achieve the adaptive immunity as we did in the pre-clinical Lassa fever model, there definitely may be a situation where the HIV is defeated by the adaptive immune system and the treated patient also becomes resistant to re-infection.

sunstar