Replies to post #52266 on Biotech Values

[DewDiligence]

> GPCB – I do realise that anything can happen, it's just I don't buy the company line of looking at the "mature" subgroup.<

Neither do I. Presenting this 12-month subgroup was a transparent attempt to dissuade ODAC from voting to wait for the full dataset. It didn’t work but, from the company’s standpoint, it was worth trying.

[iwfal]

But this doesn't seam to hold up (even as a speculative argument). The problem is that the "mature" subset curves seperate quite well by 26 weeks, while the ITT curves have no seperation through 1 year.

This is completely correct. You understand correctly how KM curves work. I made the same observation when the data first came out. For this reason, the odds that OS will be stat sig are not good.