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DewDiligence

08/24/07 4:54 PM

#4787 RE: vinmantoo #4784

Even of there’s an MoA justification for thrombomodulin + antithrombin combination therapy in DIC, it’s a risky proposition from a business standpoint until there are phase-3 data for one or both drugs as a standalone agent. The problem with combination testing at an earlier stage is that a safety problem could end up tainting both drug programs even if each drug is perfectly safe on its own.

Further down the road, combination testing might make sense, however. Regards, Dew

lake11

08/24/07 4:56 PM

#4789 RE: vinmantoo #4784

I had a limit order in for 25,000 at 1 and 19,200 was filled.