Replies to post #50166 on Biotech Values

[walldiver]

I don't know what the p value or HR will need to be for satra to hit stat sig. I would imagine that the p value would need to be 0.04-0.05. I think the interim overall survival p value based on the ~440 deaths was in the 0.25-0.30 range...would hope someone more familiar with GPCB/SPPI could confirm this, and also the approx date for that 440th death. I don't think it will be stat sig, but you never know. There could be some surviving outliers in the satra arm who end up forming a long tail on the curve, which looks like the only chance it has to attain stat sig.