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walldiver

05/17/07 3:04 PM

#3662 RE: eagle-eye #3655

Let's say the 180th event takes place in July 2008, and enrollment is completed in Sept 2007. There will be a lot of survivors in both arms who enrolled 10-15 months prior to 7/08. These patients still need to be counted in the overall intent to treat survival analysis...so there won't be much of a difference in the survival curves for these recent enrollees...thus hurting the overall p value.