HL has one of the best prognosis for cure, but relapsed/refractory HL has one of the worst prognosis (even with checkpoints and adcetris helping some of these patients), so you have a mostly young population that is desperate. Still odd to have this kind of behavior in a clinical trial setting
Almost every HL pt at this stage has seen Adcetris already. Many now first line, but if not in first line in the relapsed setting. However there is data showing response to retreatment with Adcetris so it can buy some time in some as far as I know