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sunspotter

04/29/24 2:39 AM

#402651 RE: Empiricst1 #402650

Thanks for posting this.

The key point to note is that is usual with in vitro brilacidin tests an inoculum was used.

That is to say brilacidin was already present when the potential pathogen was introduced.

The implication of this is that if brilacidin were to be employed clinically it would have to be administered prophylactically, that is before exposure to the pathogen had occurred.

It’s probably a tad impractical to administer IV brilacidin requiring an in-patient procedure to a healthy population as a precautionary measure, especially as well over 70% of those receiving it would experience either hypertensive spikes or peripheral neuropathy. Or both.

On the other hand brilacidin is useful to add to the publication list of post-grads eager to curry favor with their supervisor.
Bearish
Bearish

loanranger

04/29/24 10:15 AM

#402659 RE: Empiricst1 #402650

"Has anyone popped the $26 or so bucks for a copy of the article?"
Why do that when you can download it from the linked page?

Empiricst1

04/29/24 3:32 PM

#402666 RE: Empiricst1 #402650

Tell you what, why don't you press the download and post. I pulled what I could
and can pull no more with my computer.