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sunspotter

01/10/24 10:25 AM

#401168 RE: PJ007 #401167

Thanks for the link!

This explains why brilacidin doesn't work in vivo:

"The inhibitory potential of brilacidin against the viruses tested in this study was dependent on the dosing strategy which necessitated compound addition pre- and post-infection, with addition only at the post-infection stage not eliciting a robust inhibitory response."



Of course, the IV nature of brilacidin and its adverse event profile preclude its use for pre-exposure prophylaxis.
Bearish
Bearish

thttlpckg

01/10/24 2:34 PM

#401170 RE: PJ007 #401167

Funding
This research was funded in part by Defense Threat Reduction Agency (DTRA), grant number HDTRA11810041 to A.N.

Is this significant?

kfcyahoo

01/10/24 11:34 PM

#401174 RE: PJ007 #401167

From your post, at the bottom :
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Put your pj’s on. This “stock” is beyond sleep mode, it’s been long dead.

I check this site out for an occasional chuckle… you did not disappoint. TY for the laugh.

GLTA