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Fred Kadiddlehopper

12/01/23 8:49 AM

#7883 RE: maumar #7881

If anyone could just use plain old hyaluronidase in reformulating a drug to a subcu version, HALO wouldn't exist as a company. This leaves me wondering what exactly Merck has in their enzyme....

OncoJock

12/04/23 2:00 PM

#7898 RE: maumar #7881

Maybe Merck hopes to extend the patent protection on Keytruda through a novel co-formulation?

Also wondering if Merck could try to use a novel co-formulated product to sidestep a future requirement to negotiate price of Keytruda with Medicare contained in the Inflation Reduction Act?

-- OJ