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loanranger

08/31/23 4:13 PM

#399230 RE: frenchbroad #399227

"No one else has a good new one to speak about." Interesting deduction.
And he has less than 25 minutes to talk about it. Think he can fit in ALL the good news about the pre-clinical B anti-fungal testing?

zandant

08/31/23 6:14 PM

#399245 RE: frenchbroad #399227

Hopefully, they will do better than they did at the military symposiums.

olden_grumpini

09/01/23 11:58 AM

#399255 RE: frenchbroad #399227

The Dr. Goldman Brilacidin presentation in the October TIMM congress is the only presentation on a particular anti-fungus drug for all of the congress.


Check out the Saturday symposium: “Symposium 8, Clinic meets Pharmacology: Antifungal treatment”? There will be several presentations on single drugs, including:

S08.4, Synergistic anti-fungal activity of new, inhaled opelconazole with systemic posaconazole on Mucor circinelloides in an in vitro human alveoli model (abstract)
S08.5, Olorofim treatment of mould IFD in patients with limited or no treatment options: Results from a Phase 2b open-label study (abstract)
S08.6, SCY-247, a Second-generation IV/Oral Triterpenoid Antifungal: In Vitro Activity Against Broad-spectrum of Fungal Pathogens, and Dose-Dependent Tissue Distribution In Vivo (abstract)


There are more single-drug presentations on Sunday:

S23.4, In-Vitro Synergy of Amphotericin-B and the Novel Antifungal Drug Ibrexafungerp: A Potential New Paradigm in the Therapeutic Approach against Talaromycosis (abstract)
S23.5, Once-weekly rezafungin versus daily caspofungin to treat intra-abdominal/peritoneal invasive candidiasis: ReSTORE and STRIVE pooled subgroup analysis (abstract)


I get it that you've got a lot of your money invested in IPIX, but making stuff up isn't going to help anyone. There is still room for brilacidin to shine if it works in a human being. We should all be frustrated that so little progress has been made in this area. Commercialization is time-sensitive. The science may continue, but the commercial potential declines day-by-day. Licenses and patents expire and what was once a promising asset becomes worthless.