n=32 for the full dataset reported today, including patients with three types of STS; n=9 for the DDLPS subtype.
Curiously, the PR does not cite the ORR data, even though ORR was the primary endpoint!
APGN is enrolling an expansion cohort specifically for DDLPS, with the goal of running a phase-3 trial in this indication if the expansion cohort performs as well as the initial (n=9) cohort.
No drug regimen works well in STS, and DDLPS is probably the least responsive to treatment of any STS subtype.
-- APGN is being acquired by PYXS for a paltry $16M (#msg-171981599). PYXS presumably saw the dataset reported today before pulling the trigger.
p.s. A friend of mine died from DDLPS in 2018. He had enrolled in a pilot NKTR-214 + Opdivo STS trial conducted by MSKCC, but never received the first treatment. (The trial ended up failing, and we all know what became of NKTR-214.)