Replies to post #260 on Fate Therapeutics Inc (FATE)

[jondoeuk]

Depends on the edits. The authors go on to say limited survival of transferred human NKs is due to lack of homeostatic cytokine signaling. I know some are adding IL-15/IL-15Ra complexes, but these papers show that sustained stimulation impairs cell functions https://insight.jci.org/articles/view/96219 https://www.pnas.org/doi/10.1073/pnas.1012128107