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sks144

02/15/23 3:55 PM

#245528 RE: iwfal #245525

Those are all fair points. Do you think the P3 in TNBC will fail? I wonder why they structured it this way
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sks144

02/27/23 8:43 PM

#245683 RE: iwfal #245525

Thinking through this more- aren’t most CRC tumors CDK 4/6 dependent, vs SCLC and TNBC? Why did they think this wouldn’t be a major risk to efficacy? Because they thought they could offset the toxicity of the 5FU and allow for greater exposure?

Makes me slightly more optimistic on TNBC