Replies to post #245074 on Biotech Values

[DewDiligence]

I wish ENTA would run another P2… The current [phase-2] will leave many questions unanswered.

Speed is of the essence, so it’s impractical for ENTA to run multiple phase-2 trials that try to answer too many questions. Moreover, the MoA of EDP-235 is well understood, which lessens the potential benefit from gathering mountains of data in phase-2 in order to help de-risk phase-3.

[vinmantoo]

I pray E-235 will stop transmission. Why ENTA is recruiting unvaxxed who might have developed natural immunity in the P2 only?

Natural immunity? What are you talking about? Why in the world are you suggesting ENTA should be worried that unvaccinated people might have been infected at some point in the past?

I wish ENTA would run another P2 to recruit any non-hospitalized adult with mild or moderate COVID-19 and symptom onset within 5 days who have been vaccinated > 3 months.

Once again, what are you talking about? You want ENTA to use people who were vaccinated > 3 months ago but are unhappy they are using unvaccinated people because they might have been infected in the past. Your thread makes no sense.