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cowtown jay

01/04/23 3:55 PM

#38052 RE: dloggold #38051

LIVE-AIR trial

Placebo Comparator: Placebo Arm:

Drug: Standard of Care
Standard of care therapy can include remdesivir and/or dexamethasone per institutional treatment guidelines or written policies

https://clinicaltrials.gov/ct2/show/NCT04351152?term=lenzilumab&draw=2&rank=3

ACTIV-5 trial

Active Comparator: Remdesivir + Placebo:

Other: Placebo
Placebo for lenzilumab is commercially sourced 0.9% sodium chloride.

Drug: Remdesivir
Remdesivir is a single diastereomer monophosphoramidate prodrug designed for the intracellular delivery of a modified adenine nucleoside analog GS-441524.

https://clinicaltrials.gov/ct2/show/NCT04583969?term=lenzilumab&draw=2&rank=4

The ACTIV-5 trial really compared Remdesivir + Lenzilumab, to Remdesivir + Placebo