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cowtown jay

09/30/22 1:22 PM

#37547 RE: Mr. C #37546

You want to give management crap for doing such a "terrible job," right? What THEY did was to achieve a successful Phase III trial outcome. What THEY did was to prove a causal relationship between elevated levels of GM-CSF and CRP, to disease severity. What THEY did was to show unparalleled treatment outcomes, especially for the Black and African/American population.

My question is, did they discover a cure for Covid, when administered early in the disease progression? How many lenz patients, treated while in ordinal scale 4 or 5, suffered breakthrough infections?

I really want to see the ACTIV-5 Final Report. NIAID may have chosen to include patients in their trial that were in ordinal scale 7, but by their own trial criteria, the primary outcome is not to be measured against patients who had progressed to that stage at baseline.

"Primary Outcome Measures

Occurrence of mechanical ventilation or death at any point through Day 29 in subjects with ordinal scores of 5 or 6 at baseline"

https://clinicaltrials.gov/ct2/show/NCT04583969?term=lenzilumab&draw=2&rank=4