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sunspotter

09/19/22 9:59 AM

#393418 RE: thekidzcollegephund #393417

Thanks.

For (I think) the first time, the site now has the full protocol, which can be seen here:

https://clinicaltrials.gov/ProvidedDocs/97/NCT04784897/Prot_000.pdf

It provides at least a clue as to why the death rate in all arms was comparatively low:

Exclusion criteria:

"Requiring invasive mechanical ventilation and/or extracorporeal membrane
oxygenation (ECMO) at the time of randomization.
• Has explicitly expressed the wish not to receive intensive care support (Do not
resuscitate or Do not intubate order) should this become necessary.
• In the opinion of the investigator, progression to death is imminent and inevitable
within the next 72 hours, irrespective of the provision of treatment, such as rapidly
progressive multiorgan failure
."
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StockJumper25

09/19/22 11:20 AM

#393421 RE: thekidzcollegephund #393417

Thanks for this update and link: If you pull up other outcomes analysis there appears to be some significant changes (must do a side-by-side comparison) to the clinical documentation.
More favorable as far as we can tell, on the same data taken. I thought that there were more deaths due to the conditions of health status for subjects.

I could be reading the data wrong.

Thanks!