Institutions can certainly buy OTC unless a fund restricts it. But they usually wait since they have to report their activity to investors or bosses and they want to keep their jobs. Case point: ALPP - Before uplist to NASDAQ, 2 tutes' onboard. ALPP - After uplist, magically 62 tutes' bought. Vanguard over 1.6 million shares is the largest.
Retail has no money. It was all stolen by the Biden administration. So until more stimulus checks are given out I don't see much happening in the overall market or crypto other than Bitcoin because the rich play there now. This seems like a winner due to their actual revenue which most penny stocks do not have.