Replies to post #243646 on Biotech Values

[imnot6]

What, no survey :^D ?

I'll get it but not immediately on release as it'd be nice to get some non-mouse data. On the other hand I won't wait long as I've never been infected, well out from my 1st booster* and a higher-risk age, so the risks are increasing as my antibody titer keeps decreasing (and BA.5 continues to spread with as little as a brief pass-by with someone infected.)

* Was concerned about a 2nd making me have to wait too long for a BA.5-capable shot, along with concerns as to whether #2 booster would even make a significant difference or maybe (unlikely) even a negative one (the whole "original antigenic sin" worry).

Still N95-ing it when in the presence of any others than a select few. And yes, the risk of harm is probably greater with every passing nose-in-their-phone motorist, but still worth the precaution for me for the time being IMO.

Here's hoping we get closer to a general pan-COVID vaccine; as many say we're not going to boost our way out of this chasing variants.

[vinmantoo]

I got my second booster in mid-April. I will probably wait a few more months so I can get the hybrid vaccine before the holidays.

[SJEmmerich]

Definitely. Sometime before my son's wedding in late October. Haven't had COVID yet. Don't want it now.

[willyw]

I am nearing 70 years, but in better than average shape. Even so, with aging comes diminished immune response and greater risks with covid.

During delta (speaking generally) the risks of death or serious consequences may have been on the order of 20x greater for unvaxxed versus fully vaxxed/boosted.
(in the rear view mirror we will probably have better data on breakdown on age/comorbidity/number of shots & boosters-it's more like a spreadsheet material answer)
The answer today I recently saw was estimated as a 4x greater chance-unvaxxed versus vaxxed. The reasons are many- could be less serious effects of the newest variants or the vaccines are not providing as much coverage for even those vaxxed- less differentiation between groups.

I got my second booster in May and believe that I had covid in June roughly 6-7 weeks afterwards. I was down for about a week, never tested positive (in my delerium I may not have administered the test correctly) but had similar sides as my daughter and son in law who also had it- one before and one after I did. I had no serious after effects- and at 70ish, that is in the win column so far as I am concerned. Even if the risk factor NOW is only a factor of 4 with current vaccines that's better odds- to my way of thinking.

Will I get the co-valent? Sure.
But I can wait a little since I was boosted in May and also may have natural immunity from a presumed June infection. I am presuming that a co-valent/more specific vaccine will raise the factor above the current factor of 4 (once again- merely one estimate I recently saw-speculative).
Equally important- it may provide more protection if another delta like variant might come around the pike.

[Biowatch]

I am.

[rwwine]

I plan on getting it as well. My last booster was mid-April. If I understand correctly, the earliest I can get this new booster is mid-October.

[marthambles]

I am. Unfortunately it won't be in time for a trip abroad planned for next week.

[chantillylive]

Maybe post November. December?
Did get Booster #1. Not #2.

Will wait for the human testing. Testing will probably start next week after CDC's rubber stamping.

R.
cl

[randychub]

I’ll get it but probably wait awhile since I had Covid ba5 not long ago.

[WorstLuck]

Will be getting, sooner rather than later.

[oc631]

Who here is planning to get one of the bivalent COVID boosters? If not, why not?

I suspect you are trying to gauge demand. Demand will be partially driven by the simple fact that bivalent boosters may only be free for a limited time in the U.S. Sure the out of pocket price (OPP) for a booster in 2023 may be nominal but whether paying OPP or through insurance claims (time value) people will seek free boosting in 2022.

Having the U.S. government options for more doses with PFE/MRNA is a nice development for investors in case we have a hard COVID winter. It will take very little political pressure to find the money to make this happen.

As for myself I hope to get my first boost this month before I'm headed overseas for the winter.

[Biowatch]

Make sure you get “new” booster rather than original one. Many places are still offering the “old” booster designed to protect against the original strain.

You should ask to make sure that you are getting the redesigned shot that also targets the Omicron variant if that’s what you want.

[xavierprivas]

We plan to get it in November. My wife (67) and I (65) got 4th booster shot in May so
just want to wait a while.

[SJEmmerich]

Dew - are you going to answer your question?

steve
------------------------
Who here is planning to get one of the bivalent COVID boosters? If not, why not?

[biocqr]

Durability of Booster mRNA Vaccine against SARS-CoV-2 BA.2.12.1, BA.4, and BA.5 Subvariants

https://www.nejm.org/doi/full/10.1056/NEJMc2210546?query=TOC