Yes in a small subgroup it showed to work better then placebo such as remdesiver when given early before viral load has decimated patients. Luckily there were a few early on patients let in so that we now have this evidence.
"certain patient subgroups did show treatment benefits of Brilacidin for that primary endpoint. For example, patients treated early from onset of symptoms achieved sustained recovery more quickly (Brilacidin 5-dose group vs pooled placebo, p=0.03)".