Replies to post #242147 on Biotech Values

[swampboots]

Lumanity: interesting product goals:
https://www.prnewswire.com/news-releases/introducing-lumanity---an-organization-dedicated-to-accelerating-and-optimizing-access-to-medical-advances-301501260.html

[swampboots]

CMPI :Apparently oligonucleotides are moving up in supremacy for disease solutions-

Barriers of "Oligos" to be effective:
https://www.nature.com/articles/s41573-020-0075-7


https://en.wikipedia.org/wiki/Oligonucleotide

How many oligonucleotide drugs have been approved?
Currently, 13 oligonucleotide therapeutics have been granted new drug approval (NDA) by the U.S. Food and Drug Administration (FDA) for several different indications (Table 1) [20]. The underlying molecular mechanism is similar for all of these indications: a single gene mutation is responsible for these diseases.Mar 24, 2021

"Oligos"suppier:
https://www.trilinkbiotech.com/custom-rna-oligos?utm_campaign=Oligos&utm_medium=cpc&utm_source=google&gclid=CjwKCAjwu_mSBhAYEiwA5BBmf22SIQwFj8dIoqLvbFHDgNVquyMYQ2pPuCqN_d9igApkSwCCeTlM9RoCSQgQAvD_BwE

https://www.pacelabs.com/life-sciences/cmc-development/oligonucleotides/oligonucleotide-analytical?utm_term=oligo%20custom&utm_campaign=PLS+-+CMC+(Wolfe)&utm_source=adwords&utm_medium=ppc&hsa_acc=2195671737&hsa_cam=1614483538&hsa_grp=60463351665&hsa_ad=513986037741&hsa_src=g&hsa_tgt=kwd-1637447303662&hsa_kw=oligo%20custom&hsa_mt=b&hsa_net=adwords&hsa_ver=3&gclid=CjwKCAjwu_mSBhAYEiwA5BBmfx7YG7qo69K5JYm_SOHXOd1gscVZzIodNzaIy9prFrwXzV5yoMRv5RoC1cgQAvD_BwE

https://www.ixcellsbiotech.com/applications/antisense-oligonucleotide-screening?gclid=CjwKCAjwu_mSBhAYEiwA5BBmfwBYtFJmGupFoyIQJgR565JQyvFHDRL7m4cAB1BoEGVs8vXqdHkLBRoCSMsQAvD_BwE

Even today Oligos point to better RNA delivery solutions
"Other RNA therapies outside of mRNA are being developed or have been approved. Among these are antisense oligonucleotides, which modify gene expression; small interfering RNA (siRNA), which also modifies gene expression via a different mechanism; aptamers, which can bind other ligands, including RNA; and guide RNAs, used for CRISPR targeting. "


Current trends and perspectives in mRNA vaccines | Cytiva (cytivalifesciences.com)