Madrigal showed ALL of their endpoints and ALL of their p-values and ALL were significant. They has dramatically higher MDFF fat reduction than LL's 350 mg. Yes LL maybe significant better than placebo, but is much less effective than Madrigal's data showed. Being better than saline solution is the minimum hurdle. LL has to show it can be competitive with these NASH competitors -- and it was way behind. No partner would be interested in a drug in development that has results materially less effective that others in development. NASH is not going to get any partners.
mTNBC -- you tell me what the REAL trial data is. Dr. K never released it, buried it with compassionate use data (different patient population) and then an unproven "model" with bizarre results. So deceptive that the SEC and DOJ are investigating the reporting. No quality BP would touch suspicious clinical data.
If a drug does not show efficacy that is significantly greater than saline solution it is no better than saline solution PERIOD.
Cytodyn does not reveal all their data in many cases, it is impossible to really know what the data really is. No publishing of the data in a peer-reviewed journal. CoV data was misrepresented and manipulated (FDA Statement) and is under SEC/DOJ investigation. So Cytodyn has little credibility for their trial data.
Safety is important, but without efficacy it will not attract partnerships and a buyout. So far LL hasn't shown it can be attractive especially with the numerous deceptive data reports. Wouldn't bank on a partnership to "save" Cytodyn from their dire financial situation.