Common theme in this new paper (remdesivir synergy):
"The CIs at all the combination ratios fell below the red line (Figure 7A), and the fractional inhibitory concentration index (FICI) which was used to determine synergistic effects of compounds are less than 0.5 at all combination ratios (Figure 7B), suggesting brilacidin has significant synergistic antiviral effect with remdesivir in the combination therapy."
"Finally, drug combination therapy demonstrated that brilacidin has strong synergistic effect with remdesivir against HCoV-OC43 in cell culture. Overall, brilacidin appears to have appealing translational potential as a broad-spectrum antiviral for coronaviruses including SARS-CoV-2."