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Gohel Yoerselph

01/28/22 1:47 PM

#387657 RE: CallMeCrazy #387655

Common theme in this new paper (remdesivir synergy):

"The CIs at all the combination ratios fell
below the red line (Figure 7A), and the fractional inhibitory concentration index
(FICI) which was used to determine synergistic effects of compounds are less
than 0.5 at all combination ratios (Figure 7B), suggesting brilacidin has
significant synergistic antiviral effect with remdesivir in the combination therapy."

"Finally, drug combination therapy demonstrated that brilacidin has strong
synergistic effect with remdesivir against HCoV-OC43 in cell culture. Overall,
brilacidin appears to have appealing translational potential as a broad-spectrum
antiviral for coronaviruses including SARS-CoV-2."

Quotes taken from:
https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmv.27616

NIH combo trials?...

shazamm

01/28/22 2:31 PM

#387659 RE: CallMeCrazy #387655

CMC, I may have missed it on here, but what date was this research paper released?

Blue Fin

01/28/22 7:08 PM

#387673 RE: CallMeCrazy #387655

Thanks CMC, I am still curious:

What if? US Army has new COVID vaccine that works against all variants, researchers say


https://americanmilitarynews.com/2021/12/us-army-has-new-covid-vaccine-that-works-against-all-variants-researchers-say/