I never quite knew just how the super computer, Big Ben, aided in the development of Brilacidin until just recently.
Brilacidin was based on a natural anti-microbial peptide, magainins, found in African clawed toads that had shown an eerie ability to withstand bacteria and viruses. The problem was that the core of this natural peptide was not strong and led to many negative side effects.
The super computer was able to formulate a very strong core for the synthetic peptide mimic (Brilacidin) and reduce the negative side effects of it at the same time. Took a long time and lots of cash but in the long run seems to have been well worth it.
This description is in very simple layman terms of the procedure but that is what I got out of it. Hope you get the point.