Replies to post #2595 on GTC Biotherapeutics (fka GTCB)

[DewDiligence]

>1) Do the GTCB patents cover production in milk using all available promoters, or are they still limited?<

The claims appear to be broad. Here is the relevant text from U.S. patent #7,045,676 (bold-face emphasis of the word a is mine):

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…inserting into an embryo of a nonhuman mammal a DNA construct comprising a gene encoding said protein, said gene being under transcriptional control of a milk protein promoter sequence that does not naturally control transcription of said gene, said DNA construct further comprising a DNA sequence encoding a signal peptide for enabling secretion of said protein into the milk of said mammal…
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>2) If a party such as Velander can demonstrate knowledge and use of such production means before the patent was applied for, they have freedom to operate in most cases.<

This is pretty far down on my list of concerns!

>3) Up to 300 liters a year from a giant hungry sow is not a whole lot of milk.<

It beats the milk production from a chicken :-)