Phase 2: MRT5005, an inhaled mRNA for CF; phase 1: MRT5500, an mRNA vaccine for COVID-19 already partnered with Sanofi.
Viela Bio
Horizon Therapeutics
February 2021
$3,050
$3,050
Approved
Approved: Uplizna, a B cell-depleting humanized mAb for rare neuromyelitis optica spectrum disorder; phase 2: VIB4920 and VIB7734; phase 1: VIB1116.
TeneoBio
Amgen
July 2021
$2,500
$900
Phase 1
Phase 1: TNB-585, a bispecific T cell engager for metastatic castrate-resistant prostate cancer.
Five Prime Therapeutics
Amgen
March 2021
$1,900
$1,900
Phase 3
Phase 3: bemarituzumab, an anti-FGFR2b antibody.
Pandion Therapeutics
Merck & Co.
February 2021
$1,850
$1,850
Phase 1
Phase 1: PT101; TALON technology.
Constellation Pharmaceuticals
MorphoSys
June 2021
$1,700
$1,700
Phase 3
Phase 3: pelabresib, a BET inhibitor for myelofibrosis; phase 2: CPI-0209, a second-generation EZH2 inhibitor for hematological and solid tumors.
Kymab Group
Sanofi
January 2021
$1,500
$1,100
Phase 2
Phase 2a: KY1005, a human mAb targeting immune system regulator OX40L for moderate to severe atopic dermatitis.
Protomer Technologies
Eli Lilly and Co.
July 2021
$1,000
$1,000
Platform
Peptide and protein engineering platform.
Arvelle Therapeutics
Gruppo Angelini
January 2021
$960
ND
Approved
Approved: Cenobamate.
CF, cystic fibrosis; mAb, monoclonal antibody; ND, not disclosed. Data provided by DealForma, August 2021. Financials in US$ millions based on disclosed figures.