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Empiricst1

09/30/21 2:00 AM

#376635 RE: farrell90 #376632

Unsaid here is what are the odds of a twice vaccinated person (With Pfizer, for example) of getting a breakthrough infection. I've gone through the CDC and some of the more trusted entities and come up with a 1 in 5,000 or so chance of getting the disease. No doubt a lesser probability after a booster shot, and even less if a mask is worn in higher risk situations. It's all rather iffy, and using projected Israeli, Danish, Swedish or other testing and back fitting to the US is not ideal, but lots better than nothing.
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KMBJN

09/30/21 10:39 AM

#376692 RE: farrell90 #376632

The government response so far has been way too heavy on the vaccines. They do appear to take severe disease and death off the table for most, but still many are dying and we need therapeutics.

Regarding children, did you see the undercover video of the J&J exec and scientist, and what they *really* think about the J&J Covid vaccine and giving them to kids?

https://www.projectveritas.com/news/johnson-and-johnson-children-dont-need-the-f-cking-covid-vaccine-because/

I'm sad for all our kids having to deal with so much BS from adults, and wish they could just be kids and not have to worry about all this other stuff. Seeing kids playing baseball outside wearing masks everywhere (even the adults sitting 10 feet apart from each other in the fresh air) last year was surreal. Hard to know what is right for the kids sometimes. Hopefully they are resilient! Will they ever have a "normal" again (Covid/masks/vaccines, gender/race/orientation and other politics in school), or will the adults keep throwing their agenda at them? So much emphasis on safety for them, which is good, but it really can go too far sometimes. There is no perfect safety in our world. Zero Covid is impossible with mandates.

It will be great to have some decent Covid treatment options. I still think nucleotide encoded MABs given as a single IM/ID shot early in disease or even prophylactic on exposure or high risk are the way to go. DoD is funding some such work. Will see how some of these oral antivirals work before long too.

Yes, therapeutics should be a high priority, but sadly for poorly capitalized biotechs like us, we can't get much help. Hopefully the academics (Dr. Narayanan lab at GMU, others promised too) are able to get some grants for basic research, and perhaps we have someone in a clinical position kind enough to apply for money to run a trial. More likely that would be BP partner and/or government for Phase 3 if we show some promise in our Phase 2 trial.

Can't believe it will take so long to get our brilacidin Phase 2 results together, but I guess there are a lot of data and endpoints to check and analyze. What are we expecting - another 4-8 weeks now for our results, or 2-3 months after final 60 day endpoint?