Replies to Post #46 onMGC Ventures Inc (MGCV)

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Proactive - Interviews for investors

Immunic Therapeutics advances MS Drug , Phase 2 CALLIPER trial readout in April

Immunic Therapeutics Chief Scientific Officer Dr. Hella Kohlhof joined Steve Darling from Proactive to discuss the company’s progress in developing vidofludimus calcium, a novel treatment designed to combat multiple sclerosis (MS) through a unique dual mode of action. The drug offers neuroprotection, anti-inflammatory effects, and antiviral benefits, addressing key aspects of MS pathology. Dr. Kohlhof emphasized the urgent need for therapies that prevent disability progression in MS patients, helping them maintain independence for as long as possible. She explained that vidofludimus calcium achieves this by activating Nurr1 to promote neuroprotection while simultaneously inhibiting DHODH, reducing inflammation and Epstein-Barr virus (EBV) reactivation—both believed to play a role in MS development and progression. A major milestone for Immunic Inc. is approaching, with the phase 2 CALLIPER trial readout expected in April 2025. This study aims to confirm the drug’s neuroprotective effects, positioning it as a potential disease-modifying treatment for MS. Dr. Kohlhof also highlighted vidofludimus calcium’s strong safety and tolerability profile, noting that it is a once-daily oral tablet that requires no treatment monitoring, making it a convenient option for patients. Looking ahead, Immunic is also advancing phase 3 ENSURE trials for relapsing MS, expected to complete in 2026. With limited treatment options for progressive MS, Dr. Kohlhof underscored the high unmet medical need and the potential impact of vidofludimus calcium on improving patient outcomes worldwide. #proactiveinvestors #immunicinc #nasdaq #imux #MSResearch #VidofludimusCalcium #Neuroprotection #ImmunicInc #MSAwareness #CALLIPERTrial #MSBreakthrough #MSDisability #ClinicalTrials

Proactive - Interviews for investors

Graphene Manufacturing Group advances aluminium-ion battery development with key U.S. partnership

Graphene Manufacturing Group CEO Craig Nicol joined Steve Darling from Proactive to share an update as the company continues to make strides in the development of its Graphene Aluminium-Ion Battery technology, a cutting-edge innovation being pursued in collaboration with the University of Queensland and Rio Tinto under a Joint Development Agreement. Nicol told Proactive, to accelerate battery development, GMG has signed a service contract with the Battery Innovation Center (BIC) in Indiana, USA. This partnership will support the next phase of research and optimization, leveraging BIC’s state-of-the-art 40,000-square-foot facility in Newberry, Indiana. As a globally recognized innovation hub, BIC specializes in advancing battery technologies, offering end-to-end support from research and development to prototype manufacturing and low-volume production—a critical advantage for GMG as it scales up its graphene-based energy storage solutions. Nicol emphasized that collaborating with BIC allows GMG to access advanced battery manufacturing infrastructure without incurring the high capital costs of building its own pilot production facility—an investment that could exceed AU$10 million. Through this agreement, GMG will retain full intellectual property (IP) rights over the battery development work, ensuring control over its proprietary technology while optimizing BIC’s cell design expertise and battery manufacturing capabilities. By integrating BIC’s expertise into its scale-up strategy, GMG can streamline the production of sample battery cells before committing to mass production, reducing risks and deferring large capital expenditures until the technology reaches a higher level of readiness. Looking ahead, GMG aims to optimize battery performance, produce initial test cells this year, and engage customers for validation. Nicol noted strong interest from major companies eager to integrate this technology. #proactiveinvestors #graphenemanufacturinggroupltd #BatteryTech #

Proactive - Interviews for investors

Europa Oil & Gas CEO on Cloughton planning application and community engagement

Europa Oil & Gas (Holdings) Plc (AIM:EOG) CEO Will Holland talked with Proactive's Stephen Gunnion about the company's submission of a planning application for the Cloughton appraisal well in Yorkshire. The application seeks approval to drill and test a gas field originally discovered in 1986. Holland explained that advancements in technology and improved gas prices now make it viable to extract gas at commercial rates. The appraisal well will determine the feasibility of full-field development. He also discussed the launch of a dedicated community engagement website, designed to provide local stakeholders with transparent information, including independent environmental and regulatory reports. Holland emphasised that the project follows strict UK regulations and aims to minimise environmental impact. Addressing concerns, he clarified that fracking is not involved, citing confirmation from Energy Minister Michael Shanks. He also noted that increased heavy goods vehicle (HGV) traffic would be minimal, at around 1% during operations. Holland stressed the project's potential benefits, including job creation and reducing the UK's reliance on imported liquefied natural gas (LNG). “If you're concerned about the environment, you should be supporting domestic gas production. And that's exactly what this is,” he stated. For more interviews with industry leaders, visit Proactive’s YouTube channel. Don't forget to like this video, subscribe, and turn on notifications for updates! #EuropaOilAndGas #EnergySecurity #NaturalGas #UKGas #CloughtonWell #EnergyTransition #Investing #OilAndGas #SustainableEnergy #LNG

Proactive - Interviews for investors

KEFI Gold and Copper gets green light to progress with Tulu Kapi project in Ethiopia

KEFI Gold and Copper PLC executive chairman Harry Anagnostaras-Adams talked with Proactive about a major milestone for the company’s flagship Tulu Kapi gold project in Ethiopia. He described the latest announcement as the most significant since KEFI decided to focus on the Arabian Nubian Shield in 2008. Anagnostaras-Adams confirmed that all stakeholders in the project have now given the green light, marking the start of the next phase. He emphasised that there is no risk of being blocked, as land resettlement is progressing with the support of the local community. The process, involving thousands of people, is expected to be completed within a month, alongside final project preparations. He reiterated that the company has passed the “point of no return” and is now expediting the project’s launch. Investors seeking more details on KEFI’s technical, environmental, and financial studies can find extensive information on the company’s website: https://www.kefi-goldandcopper.com For more updates on KEFI Gold and Copper and other industry developments, visit Proactive’s YouTube channel. Don’t forget to like this video, subscribe, and turn on notifications for the latest insights. Relevant Hashtags #KEFIGold #GoldMining #CopperMining #TuluKapi #EthiopiaMining #MiningInvestment #GoldStocks #ResourceSector #MiningUpdates #ProactiveInvestors

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