Replies to post #6215 on InVivo Therapeutics Holdings Corp (NVIVQ)

[Frankestin]

INSPIRE 2.0: Active Pivotal Study of the Neuro-Spinal ScaffoldTM
? Encouraging data from single-arm INSPIRE 1.0 study supports follow-on study
? 20-patient (two-arm, 10 subjects in each study arm) randomized, controlled trial designed to provide
clinical data that will supplement the existing INSPIRE 1.0 clinical results
? As of September 8, 2021, 15 patients have been enrolled and 18 sites are open for enrollment
? Due to recent variability in enrollment patterns, Company is not estimating at this time when enrollment may be complete
Desire to Expand Pipeline beyond the Neuro-Spinal Scaffold with
Technologies that align with InVivo’s Core Competencies
? Ongoing Joint Research Collaboration with Q Therapeutics, Inc.: Aims to evaluate the preclinical safety and feasibility of the Neuro-Spinal ScaffoldTM with stem cells