Replies to post #17696 on Synaptogenix Inc (SNPX)

[InTheTrenches]

If AD is a real disease with no cure, why would they even respond to placebo over the short-term?

Obviously there is more at play. Some patients respond to just being treated (taking a pill or getting a shot or getting an IV infusion), whether there is sugar in the vehicle or actual drug.

[InTheTrenches]

"...sounds like data manipulation to me."

Patients are excluded from trials for many reasons.

Just look at clinicaltrials.gov...every trial has inclusion and exclusion criteria.

And, I wasn't saying exclude EVERYONE that improves, I would just exclude those who are super responders to placebo (greater than a certain threshold).

If a patient is shown to respond remarkably to placebo, seems like as good
a reason as any to exclude that patient in a neuro trial.