Replies to post #365608 on Innovation Pharmaceuticals Inc (IPIX)

[MinnieM]

Completely agree with your comment.




Message in reply to:
To the contrary: it might prove quite meaningful...

60 day follow up is meaningless.

The purpose behind the 60-day follow up is to determine/measure Brilacidin's efficacy against the so-called long haul symptoms.

If there's a statistically discernible and beneficial distinction between the treatment and placebo group with regard to long-haul morbidity (presuming the treatment group shows a lower incidence of symptoms), it would be a significant data point.

I recognize that all of the outcomes in the trial protocol are measured through day 29, but if there's clear and irrefutable benefit conferred through day 60 amongst the treatment group it won't be ignored.

[williamssc]

Thanks, good post. Per UCDavis Health One common theory about patients with long-term COVID-19 symptoms is that the virus possibly remains in their bodies in some small form. Another theory is their immune systems continue to overreact even though the infection has passed.

I hope B completely clears C-19 out of the body. Anti-inflammatory properties may also help calm the overreaction.

[loanranger]

"If there's a statistically discernible and beneficial distinction between the treatment and placebo group with regard to long-haul morbidity (presuming the treatment group shows a lower incidence of symptoms), it would be a significant data point."

No doubt. And they should be able to get some reasonably meaningful, if not perfect, data with a phone poll. At least an inkling.

But anything other than morbidity and the self-reporting over the phone stuff gets statistically less reliable.


3. Follow-up period (Day 4-6 through Day 60): Subjects will be assessed daily while hospitalized. Discharged patients will be asked to attend study visits at Days 15 and 29. A follow-up visit at Day 60(±10), by telephone call, is also included to confirm patient status.
10. Incidence of treatment-emergent adverse events [ Time Frame: Day 1 through Day 60 ]
Treatment-emergent Adverse Events (TEAEs) have onset dates on or after the study treatment start date

[To infinity and beyond!]

Such complete nonsense. Long haul COVID? While the world burns? LOL. Bogus nonsense

Hey why don't we wait to see about long haul COVID said Leo to those dying in Missouri and Arkansas and Russia and Indonesia and Brazil????

Oh- I get it- that is the only chance it'll be approved. Since it failed all important measures.

LOL