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trickledownfacists

07/09/21 10:49 AM

#40016 RE: XenaLives #40015

Correct
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exwannabe

07/09/21 12:04 PM

#40017 RE: XenaLives #40015

Testing subgroups requires some method of defining alpha allocation else something will almost always stick by pure luck. Trials have dozens of p[refined subgroups.

What if the trial had worked in high risk only? In men? I those with stage 1? In US patients? In those over 65?

There are plenty of ways to do this. But they must defined in advance.

Just looking at all the subgroups and claiming victory if one works is what DD was talking about with his M&Ms.

CVM themselves said they powered the trial at 0.05 for OS in the entire population. That is end of story.
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sab63090

07/09/21 12:27 PM

#40018 RE: XenaLives #40015

@XenaLives

Thanks for the clarification to me.

It helps me to understand where the process can go.
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Rubyred77

07/10/21 4:38 AM

#40035 RE: XenaLives #40015

Nice to see a familiar face in the crowd.

Took a shot at CVM simply on the fact that Adam.F tweeted negative about the co.
Plus $2k doesn’t buy as much AVXL as it used to.

Now it’s time to do a little DD to see if continuing to add on the current position is a good idea.