Replies to post #1405 on PDS Biotechnology Corp (PDSB)

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from pharmD on twitter

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For a second try to digest how important this data is for R/R advanced HPV malignancies.
1) 1st line Chemo and or Radiation Tx, if fails followed by CI therapy.
2) ORR is about 12-24% with Checkpoint Inhibitors for R/R cancer that doesn’t respond to chemo/radiation tx.
3) BintraFusp alfa highest ORR so far close to 30% who are CI naive.
4) BintraFusp alfa showed ORR close to 10% in advanced HPV refractory to CI therapy.
5) Now PDS0101 triplet therapy shows an ORR of 10/14 (71%). Not sure why some biotech analysts ignoring this data