Replies to post #361580 on Innovation Pharmaceuticals Inc (IPIX)

[farrell90]

Fortunately Brilacidin is not limited by these factors.

Its virucidal mechanism of action means it kills Covid19 on contact. It does not have to be converted to an active form so with infusion it kills the virus at first in the serum. With its good pharmcokinetics and high SI number it is well distributed throughout the body and kills the virus in the extracellular spaces as well as inside the cells. It was shown in the Viruses publication to block entry of Covid19 in the cells. And, computer modeling suggests it can disrupts the viral M-protein of Covid19 to prevent viral replication.

These multiple mechanisms of action, high SI number and safety all should make Brilacidin a superior antiviral, but also be active against Covid variants. It should make viral resistance much less likely.

We will know for sure soon.

GLTA, Farrell

[MaskedCat]

Also:
Remdisivir belongs to a class of antiviral drugs that work by posing as legitimate chemical building blocks of a DNA or RNA sequence. These poseurs get themselves stitched into the nascent strand and gum things up so badly that the polymerase stalls out or produces a defective product

[MaskedCat]

Just wanted to simplify a bit for for all the hub dummies like me.