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frenchbroad

05/22/21 10:40 PM

#360019 RE: farrell90 #360018

*The Pfiizer study is a phase 1 ascending dose trial in 60 healthy volunteers. This is the first time the drug has been used in humans.*
What can go wrong?
IOM

FatAlbert1986

05/22/21 10:52 PM

#360021 RE: farrell90 #360018

Protease inhibitors are the main combatants against HIV. Go and ask an HIV patient what their side effects are to common protease inhibitors and report back. I am not afraid of protease inhibitor competition. Ask yourself whether you will take Brilacidin or an HIV drug and the argument is over. EOM.

farrell90

05/22/21 10:52 PM

#360022 RE: farrell90 #360018

In contrast Brilacidin may have 3 antiviral mechanisms of action. In addition it is a proven broad spectrum antibiotic and it has anti-inflammatory properties.

Brilacidin starts killing Covid 19 in the serum shortly after infusion. It does not require conversion to an active form like Remdesivir and Pfizers PF 07321332..Brilacidin is the only antiviral being studied which is viruidal. It attaches to the viral coat and destroys the virus shortly after contact.

The Pfizer drug is a prodrug, like Remdesivir, and has to be activated to its effective form.

In addition testing at the RBL demonstrated that Brilacidin prevents viral attachment to the cells.Computer simulations showed it may deactivate the virus's main protease.

Bliacidin has a number of anti-inflammatory properties which may limit the Covid 19 inflammatory cascade which leads to many complications including pulmonary failure.

It broad spectrum antibiotic may reduce the secondary infection rate in hospitalized patients which has been reported as high as 8%

Brilacidin has been successful in all of its previous studies. The Phase 2 study is soon to be fully enrolled.

GLTA,Farrell

TradingPro

05/22/21 11:01 PM

#360023 RE: farrell90 #360018

How can it be ready EOY if in a Phase1 study? Did Rem have to show efficacy? Get the drift? I agree with everything you are saying, but somebody PFE’s anti-viral in Phase 1 will be approved and in use before B. Russia,China, and India seem to be on to the FDA and BP pay to play scheme and won’t just accept the treatment at face value . So B, is starting to garner awareness there.