Replies to post #167080 on Cytodyn Inc (CYDY)

[DonDonDonDon]

Only if the patients were given additional doses due to the half-life, IMO. Give the third dose and those 21 day numbers change. Give the 4th dose, if needed and the 28 day number changes. I guess this will be what they design the next trial to do. Interesting stuff, anyway.

No matter how the trial is conducted, you want to know if the people who were alive at 28 days survived until 42 days and 60 days. All that matters is the efficacy that you end with.

If the CD12 trial had ended at 14 days, the critical subgroup would have looked great and no one would be talking about additional doses right now.

All of the Covid trials should have had their primary endpoint at 60 days because Covid lasts for more than a month for a lot of patients. Mortality at 60 days is a super easy trial endpoint since all it involves is a phone call or three.