I take oversized positions early on, and like you said you do, I also sell half (or less if it more than doubles) once it moves higher so I can be greedy with the rest. After that, sometimes I'll sell on spikes around court dates and buy back lower if I think I can (AL*N BA*L). UVS* is an example of one I waited to buy until he gained control. I'm mostly betting on Synergy, but I will always keep some after a RM occurs in case it goes wild like a few have done this year.
Will be interesting to see how these California plays work out, two are very low O/S. Could set a precedent for future California plays since their laws are different. $AESO