If ONE can do an adaptive study and changes everything along he learns, why we didn't do? Why we are not doing now so?
The adaptive study makes a lot of sense to me but this could have made also us brining the winner. "Learning by doing". Not stupid, but then all others are stupid. FDA allows this and evaluate results in the same manner as from those who stupidly didn't do like this?
Like on the "Farm of Animals". Some pigs are more similar to other pigs.