I'm not sure of this. I'd have to see very detailed data, mainly the chemeical structure. Based on experience, I'd venture to safelty guess they are a different compound. Usually when compounds exhibit similar activity on a specific system...they tend to share extremely similar chemical backbones, with varying 'R groups." These R groups, or side groups, can vary by a single molecule, which in turn, effects a compound's activity, among a plethora of other things.
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