Replies to post #351670 on Innovation Pharmaceuticals Inc (IPIX)

[thefamilyman]

So to clarify the impact your numbers have on the premise posed by Lemoncat; when using the same cell lines, while Brilacidin had only ~half the toxicity, it also had almost five times the anti-viral capability. So comparatively speaking, and contrary to Lemoncat’s supposition, Brilacidin’s high SI in relation to Remdesivir is due primarily to it’s much higher anti-viral capacity.

RuleRationale said,

Brilacidin:
426 (CC50 = 241 µM/IC50 = 0.565 µM), Calu-3 Cells [1]

Rem:
38 (CC50 = 50 µM/IC50 = 1.3 µM), Calu-3 Cells [2]