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synaphai

03/10/21 10:50 AM

#152160 RE: Qball420 #152156

It is really a 9% reduction in mortality. The 24% is the relative reduction. According to the trial results if leronlimab were given to all of the patients on mechanical ventilation, it would save 9% of them.
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DonDonDonDon

03/10/21 10:50 AM

#152161 RE: Qball420 #152156

Results are in. 24% reduction in mortality for patients on ventilator compared to placebo. How do you call that a failure?


It is a small part of the trial. Anytime you have a trial, you'll find good results at certain spots from random luck. It is like pool. You can smash the cue ball without intent and it might knock a ball in. That is why you have to call your shot. It is the same with trials. You need to meet your primary endpoint so they know that it is not the result of random luck. 24% improvement in a part of the trial that only had 62 patients is nothing burger. Every trial has bright spots like this. The CD12 didn't hit its primary endpoint nor any of its secondary endpoints. Some people haven't been following the biotech realm for long so they are easily fooled by spin.