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02/28/21 7:18 PM

#349593 RE: JTORENCE #349591

Straight from the PR:

“After an interim review, by an independent Data Monitoring Committee (DMC), dosing may be extended to 5 days.”

So the only reason the DMC would look to extend from 3 days of Brilacidin treatment to 5 days of treatment would be because of positive developments they are seeing in those first 3 days of treatment. Some keys to the trial would be to see how quick patients get off of ventilators, how well the lung function/inflammation reduced and healing was progressing from just the 3 days of treatment.