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Cognition

02/19/21 12:06 PM

#347423 RE: To infinity and beyond! #347419

No 106 was not the plan. 120 is the plan for the multinational study. 106 is a really specific number to plan for and goes against human nature to round things off when making a plan. Like planning to dose 120 instead of planning to dose 126 or 106 or 121 or 133 or 8675309...
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Justfactsmam

02/19/21 12:30 PM

#347432 RE: To infinity and beyond! #347419

You stated:

"106 is the plan. the 20 hospitals are the plan. The plan has yet to get off the ground. Where is there any proof that it has?"



"Where is there any proof that it has?"... There is no proof it hasn't. Dates in Russian filings would lean toward trials having been commenced.

In fact, if most of the assumptions here of 106 patients and 20 sites, are correct , that would be 5.3 patients per site. So there will be 4 to 6 per site...(don't think that 30% of a patient would qualify for the trials, it would be awlful messy too!)

How long would it take for a site to locate 4 or 6 patients, who fit the trial profile, at a site in Russia ravaged with Covid-19...my guess (aka IMO) ...maybe 2 weeks at the most and add 5 days of observation continued dosage, if necessary, (that is if they don't walk out in 24/48 hours.!)

IMO on the issue of Dosing...(considered the start of trials), in Russian the TRIAL could be done or very close to complete dosing and observing in reported period, and possibly finished.

Personally I was very surprised at the 20 site trial...a brilliant move on LEO's part...doing 21-22 in 5 sites...could take 5-6 weeks per site to complete...If 106/20 is correct...it would not be unreasonable to expect Russian is done...

What about U.S. Trials? IMO, likely hear everything on Monday at the same time as 10Q filing...at least I hope so...

IMO in the next PR, we will understand why LEO was too busy not to play with a PRs...(although IMO it was another brilliant strategic move...screwing up the shorts and keeping them blinded...which may continue)

TIAB...certainly hope you can join us at $1.00. (or were you waiting until $2.00?) :-)


PS attilathehunt...love your plan..."time to sell...when the buyout" happens...I am with you...IMO success in B-C Trials will = "buyout"...