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02/18/21 11:22 PM

#36191 RE: changes_iv #36190

Nath said he was surprised to find almost all of the patients had abnormalities in the brain. He said bright spots visible on their brain scans represented areas of inflammation. Dark spots represented bleeding in the brain, which Nath said was likely a result of blood vessels leaking. https://kstp.com/coronavirus/new-study-shows-some-covid-19-patients-end-up-with-damage-to-brains-february-15-2021/6014166/

The cerebral protein levels of VEGF and VEGF expression in the SVZ were also enhanced in VIP-treated rats at 7 days after stroke. VIP treatment obviously increased the number of BrdU positive endothelial cells in the SVZ and density of cerebral microvessels in the ischemic boundary at 28 days after ischemia. Our study suggests that in the ischemic rat brain VIP reduces brain damage and promotes neurogenesis by increasing VEGF. VIP-enhanced neurogenesis is associated with angiogenesis. These changes may contribute to improvement in functional outcome. https://europepmc.org/article/med/26363093