Replies to post #147178 on Cytodyn Inc (CYDY)

[Leronlimab4DaWin]

It’s quite simple:
1) the inclusion criteria for CD12 is such that it ignores the “sickest of the sick”
2) comparable critical mortality rates for CD12 is 30-35%
3) comparable severe mortality rates for CD12 is 10-12%
4) in order for LL to achieve a p-value < 0.05 (stat sig) the placebo arms needs to have >31% death rate assuming 90 total trial deaths after 28 days
5) 4 is not possible given 2&3 and the fact that the trial was not stopped due to efficacy when there were 45 total deaths out of 195.