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CallMeCrazy

01/25/21 11:31 AM

#341440 RE: DaubersUP #341385

Nice find. Supports Leo's position on B-ABSSSI

Leo has stated the goal of his strategy for development of IPIX"s many indications is to "maximize value".

The broken antibiotic market was not and is not conducive for IPIX receiving maximum value for B-ABSSSI and thus it had to be shelved.

The broken antibiotics market

The pipeline of new antibiotics is running dry, because the market for antibiotics is broken. The development costs for newly approved antibiotics cannot be covered through sales. Most of the major pharmaceutical companies have stopped developing new antibiotics, and many smaller enterprises have folded due to the lack of a sustainable economic model.

The main reason is that newly developed, effective antibiotics are being used as a ‘last resort’ in the hospital sector: they are sensibly kept locked away in the medical cabinet, only to be used if the cheap generics fail. Of course, this is damaging to the
manufacturers’ incentive, as it undermines the possibility to make revenues from new antibiotics.
(emphasis added)

The solution requires political intervention to reconstruct the market and make the development and production of antibiotics profitable again. We need to change the way we value antibiotics to make-up for costly development.


https://www.weforum.org/agenda/2021/01/covid19-antimicrobial-resistance-prevention/

According to the above-referenced article: "The prevalence of AMR will likely increase through the heavy use of antibiotics in COVID-19 patient treatment."

This will further increase the need for governments and corporations to resort to financial remedies for the AMR problem. As the article points out: " The AMR Action Fund has raised US$1 billion from major pharmaceutical companies and foundations to invest in biotech. The aim is to bring as many as four new antibiotics to patients by 2030." (emphasis added)

Leo was wise to hold up B-ABSSSI. He knows the grass will be greener later (maybe much greener due to COVID-19).