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11/29/20 3:32 AM

#3845 RE: BIGKAHUNA57 #3840

4+US Hospitals & 5TH Canadian Hospital Q4 2020!!

Clinical study site status. The Company has successfully launched four CSSs and is preparing to launch a fifth Canadian CSS later in the year. The Company is in advanced discussions to launch a number of U.S. based CSS, subject to the United States economy recovering from the COVID-19 pandemic. The U.S. based Trial Management Organization is supporting the of launch 4 to 5 CSSs in 4Q2020 with potential to commence Study II patient enrollment and treatment as early as 1Q2021.

November 27, 2020